Testosterone cypionate: Uses, Interactions, Mechanism of Action DrugBank Online

Call your doctor for instructions if you miss an appointment for your testosterone injection. Do not use testosterone if you are pregnant or may become pregnant. Tell your doctor right away if you become pregnant during treatment. Use effective birth control while you are receiving this medicine. Testosterone injection is also used “off-label” for the treatment of gender dysphoria.

• Data sources include Micromedex (updated 4 Feb 2024), Cerner Multum™ (updated 4 Feb 2024), ASHP (updated 10 Jan 2024) and others.
• The present report is concerned with a comparison, in hypogonadal men, of the effectiveness of oil solutions of this material and of testosterone propionate.
• In children, androgen treatment
  may accelerate bone maturation without producing compensatory gain in linear growth.
• 1938 saw the FDA approve testosterone for use, and 1939 saw its first use.

Two years later, Schering AG in Germany made it available for therapeutic usage. It was sold under the trade name Testoviron and combined with testosterone enanthate. Prior to 1960, this type of testosterone dominated the market for prescription medications in the United States and was also the first one that was commercially available there. Androgen therapy, such as testosterone, can result in loss of diabetic control and should be used with caution in patients with diabetes mellitus. Testosterone propionate was first described in 1935 to increase synthetic testosterone’s therapeutic usefulness by slowing its release into the bloodstream. It was released for clinical use two years later by Schering AG in Germany, featured in a hybrid blend with testosterone enanthate under the brand name Testoviron.

IM Administration

When filling your prescription, be sure to call ahead to make sure your pharmacy carries it. Testosterone cypionate should not be used by people who are breastfeeding or chestfeeding. Testosterone cypionate is available as the brand-name drug Depo-Testosterone. In some cases, they may not be available in every strength or form as the brand-name drug. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records.

• Theoretically, because the soy isoflavones appear to inhibit type II 5-alpha-reductase, the soy isoflavones may counteract the activity of the androgens.
• If you think you’ve taken too much of this drug, call your doctor or local poison control center.
• In 1991, testosterone, along with a number of anabolic steroids, received a restricted drug designation.
• Testosterone Cypionate Injection contains testosterone, a Schedule III controlled substance in the Controlled
  Substances Act.
• Metal components contained in the backing of some transdermal systems can overheat during an MRI scan and cause skin burns in the area where the patch is adhered.

In September 1995, the FDA initially approved testosterone transdermal patches (Androderm); many transdermal forms and brands are now available including implants, gels, and topical solutions. A testosterone buccal system, Striant, was FDA approved in July 2003; the system is a mucoadhesive product that adheres to the buccal mucosa and provides a controlled and sustained release of testosterone. In May 2014, the FDA approved an intranasal gel formulation (Natesto). A transdermal patch (Intrinsa) for hormone replacement in women is under investigation; the daily dosages used in women are much lower than for products used in males. The FDA ruled in late 2004 that it would delay the approval of Intrinsa women’s testosterone patch and has required more data regarding safety, especially in relation to cardiovascular and breast health.

Important considerations for taking testosterone cypionate

Users of this information are advised that decisions regarding the use of drugs and drug therapies are complex medical decisions and that in using this information, each user must exercise his or her own independent professional judgment. Neither ASHP nor the University of Utah assumes any liability for persons administering or receiving drugs or other medical care in reliance upon this information, or otherwise in connection with this Bulletin. Neither ASHP nor the University of Utah endorses or recommends the use of any particular drug. Any application of this information for any purpose shall be limited to personal, non-commercial use. Other prescription and over-the-counter medicines, vitamins, and herbal products may also react with testosterone.

• The dosage is based on your medical condition, testosterone blood levels, and response to treatment.
• The secretion of androgens from the adrenal cortex is insufficient to maintain male sexuality.
• Here you will find options to view and activate subscriptions, manage institutional settings and access options, access usage statistics, and more.
• Testosterone propionate is a prodrug of testosterone and is an androgen and anabolic–androgenic steroid (AAS).
• Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects.
• Two years later, Schering AG in Germany made it available for therapeutic usage.

Because some testosterone transdermal systems (e.g., Androderm) contain aluminum or other metal components, patients should be instructed to remove the patch before undergoing magnetic resonance imaging (MRI). Metal components contained in the backing of some transdermal systems can overheat during an MRI scan and cause skin burns in the area where the patch is adhered. Testosterone propionate possesses a relatively short half-life compared with other testosterone esters at approximately 4.5 days. Testosterone propionate is a slow-release anabolic steroid no longer used commonly for the treatment of androgen deficiency or promotion of anabolic effects on muscles. Testosterone propionate is a prodrug of testosterone and is an androgen and anabolic–androgenic steroid (AAS). It is not known whether testosterone passes into breast milk or if it could harm a nursing baby.

Testosterone Propionate (CIII), Micronized, USP

Various dosage regimens have been used to induce pubertal changes in hypogonadal males; some experts have
advocated lower dosages initially, gradually increasing the dose as puberty progresses, with or without a decrease
to maintenance levels. Other experts emphasize that higher dosages are needed to induce pubertal changes and
lower dosages can be used for maintenance after puberty. The chronological and skeletal ages must be taken into
consideration, both in determining the initial dose and in adjusting the dose.

For Testosterone Replacement Therapy, timing and frequency of injections are just as important as the ester. The ultimate goal should be to restore total Testosterone to an optimal range, with about 2%-4% free Testosterone in the blood. Compounded ester combinations can offer multiple effects for more balanced levels. For example, a Propionate/Cypionate blend can optimize levels quickly due to the Propionate, while offering more stabilized levels over time due to the longer-acting Cypionate. This ester is one of the longest acting, with studies showing that Testosterone levels remained elevated for roughly three months post-injection. While each patient responds differently to medication, the starting dose is often 100 to 200 mg injected intramuscularly every 5-7 days.

Injections are typically administered every 2-3 days to maintain consistent levels. Androgens should be provided concurrently with other hepatotoxic drugs with caution because they can enhance the risk of hepatotoxicity. Particularly for those with a history of liver illness, patients should be constantly watched for symptoms of liver damage.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Rarely, males https://streetfooddenmark.com/drostanolone-steroid-dosage-experts-warn-of/ may have a painful or prolonged erection lasting 4 or more hours. If this occurs, stop using this drug and get medical help right away, or permanent problems could occur.